Prostase vaccine

Details Prostase vaccine Prostase vaccine

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 31/70 (2006.01) A61K 39/00 (2006.01) C07K 14/11 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12N 9/64 (2006.01)

Patent

CA 2378846

The present invention relates to novel proteins and to their production, from the prostase family. In particular, the invention pertains to a prostase protein or fragment thereof fused to an immunological fusion partner, such as NS1. Such antigens may be formulated to provide vaccines for the treatment of prostate tumours. Novel methods for purifying prostase protein and homologues are also provided.

La présente invention concerne de nouvelles protéines et leur production, à partir de la famille de prostases. En particulier, l'invention a pour objet une protéine de prostase ou un fragment de cette dernière, liée à un partenaire de fusion immunologique, comme le NS1. Ces antigènes peuvent être formulés pour obtenir des vaccins pour traiter des tumeurs de la prostate. L'invention a aussi pour objet de nouveaux procédés permettant de purifier la protéine de prostase et les homologues.

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