Prostate cancer drug screening

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C12Q 1/02 (2006.01) C12Q 1/66 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2262438

Screening of compounds for activity toward inhibition of prostate cancer cell proliferation is provided. A cell line is employed which can be used in conventional equipment for determining activity of compounds, where the cell line uses a marker whose expression is responsive to therapeutically active compounds.

On décrit le criblage de composés en vue de rechercher chez ceux-ci une activité d'inhibition de la prolifération des cellules du cancer de la prostate. On emploie une lignée cellulaire que l'on peut utiliser dans un matériel classique de détermination de l'activité de composés, dans lequel cette lignée cellulaire utilise un marqueur dont l'expression est sensible à des composés actifs sur le plan thérapeutique.

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