C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2719172
Alterations in ERG gene expression can be observed in patients with prostate cancer. Specific ERG isoforms are associated with, or involved in, prostate cancer. Compositions comprising these isoforms provide therapeutic benefit and can be used in methods of detecting, diagnosing, prognosing, and treating prostate cancer. These compositions provide biomarkers for detecting the expression of combinations of the PSA/KLK3, PMEPA1, NKX3.1, ODC1, AMD1, and ERG genes.
Des altérations dans l'expression du gène ERG peuvent être observées chez les patients atteints du cancer de la prostate. Des isoformes ERG spécifiques sont associées à, ou impliquées dans le cancer de la prostate. Des compositions comprenant ces isoformes fournissent un bénéfice thérapeutique et peuvent être utilisées dans des procédés de dépistage, de diagnostic, de pronostic, et de traitement du cancer de la prostate. Ces compositions fournissent des biomarqueurs pour détecter l'expression de combinaisons des gènes PSA/KLK3, PMEPA1, NKX3.1, 0DC1, AMD1, et ERG.
Dobi Albert
Petrovics Gyorgy
Sreenath Taduru
Srivastava Shiv
Sun Chen
Kirby Eades Gale Baker
The Henry M. Jackson Foundation For The Advancement Of Military Inc.
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