Prostate-specific gene, pcgem1, and methods of using pcgem1...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12N 9/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2368385

A nucleic acid sequence that exhibits prostate-specific expression and overexpression in tumor cells is disclosed. The sequence and fragments thereof are useful for detecting, diagnosing, preventing, and treating prostate cancer and other prostate related diseases. The sequence is also useful for measuring hormone responsiveness of prostate cancer cells.

Cette invention concerne une séquence d'acide nucléique qui présente une expression et une surexpression prostatiques spécifiques dans les cellules tumorales. Cette séquence et des fragments de cette séquence sont utiles pour la détection, le diagnostic, la prévention et le traitement du cancer de la prostate et d'autres pathologies en rapport avec la prostate. Cette séquence permet également de mesurer la réceptivité hormonale des cellules du cancer de la prostate.

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