Prostatic cancer vaccine

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61K 39/395 (2006.01) C07K 16/42 (2006.01)

Patent

CA 2168952

Vaccines capable of eliciting an immune antitumor response for prostate tumors are disclosed. The active ingredient in such vaccines is selected from the group consisting of: at least one antigen over-represented in the prostate gland or an immunologically effective portion thereof; an expression system capable of generating in situ said antigen or portion; a naked DNA encoding said antigen or portion; and an antiidiotypic antibody or fragment thereof which mimics said antigen or portion.

Vaccins capables de provoquer une réponse immunitaire antitumorale dans le cas de cancers de la prostate. L'élément actif de tels vaccins est sélectionné dans un groupe consistant en: au moins un antigène surreprésenté dans la prostate, ou l'une de ses portions immunologiquement efficace; un système d'expression capable d'engendrer in situ lesdits antigènes ou leurs portions; un ADN nu codant pour lesdits antigènes ou leurs portions; un anticorps antiidiotype ou l'une de ses portions capable de mimer lesdits antigènes ou leurs portions.

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