Prosthesis for promoting the in vivo reconstruction of a...

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/56 (2006.01) A61L 27/38 (2006.01)

Patent

CA 2696531

The invention relates to a prosthesis for promoting the in vivo reconstruction of a hollow organ or a portion of a hollow organ, characterised in that it comprises: a biodegradable hollow tubular bearing including at least one biocompatible and biodegradable polymer material, said bearing having an outer porous layer and an inner substantially non-porous layer and a material from a living biological origin on the outer surface and/or inside at least one portion of the porous layer of said bearing and/or on the surface of the substantially non-porous layer opposite the porous layer, wherein said material from a biological origin is selected so as to allow the in vivo reconstruction of said organ or said portion of the organ. The invention also relates to a method for producing such a prosthesis and to the medical applications thereof in particular for reconstructing a portion at least of a hollow tubular organ, in particular the oesophagus.

L'invention concerne une prothèse destinée à promouvoir la reconstruction in vivo d'un organe creux ou d'une partie d'un organe creux, caractérisée en ce qu' elle comprend : un support tubulaire creux biodégradable comprenant au moins un matériau polymère biocompatible et biodégradable, ledit support comprenant une couche externe poreuse et une couche interne essentiellement non poreuse et, un matériau d'origine biologique vivante à la surface externe, et/ou ou au sein d'au moins une partie de la couche poreuse dudit support, et/ou sur la surface de la couche essentiellement non poreuse faisant face à la couche poreuse, ledit matériau d'origine biologique étant choisi pour permettre la reconstruction in vivo dudit organe ou de ladite partie d'organe. L'invention concerne une méthode de production d'une telle prothèse et ses applications médicales notamment pour reconstruire au moins une partie d'un organe tubulaire creux, en particulier d'un oesophage.

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