Prosthetic intervertebral disc

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/00 (2006.01) A61F 2/44 (2006.01) A61L 27/20 (2006.01) A61L 27/22 (2006.01) A61L 27/24 (2006.01) A61L 27/26 (2006.01) A61L 27/46 (2006.01) A61L 27/48 (2006.01) A61L 27/54 (2006.01) A61L 27/58 (2006.01) A61F 2/00 (2006.01) A61F 2/02 (2006.01) A61F 2/28 (2006.01) A61F 2/30 (2006.01) A61F 2/38 (2006.01) A61F 2/42 (2006.01)

Patent

CA 2082427

A prosthetic intervertebral disc (200) is disclosed which can be implanted in the human skeleton, and which can at as a scaffold for regrowth of intervertebral disc material. The disc (200), includes a dry, porous, volume matrix of biocompatible and bioresorbable fibers which may be interspersed with glycosaminoglycan molecules. The matrix is adapted to have in vivo an outer surface contour substantially the same as that of a natural intervertebral disc, whereby said matrix establishes an at least partially bioresorbable scaffold adapted for ingrowth of intervertebral fibrochondrocytes. Cross-links may be provided by a portion of the GAG molecules.

Disque intervétébral prothétique pouvant être implanté dans le squelette humain, et agissant comme une greffe servant de support à la recroissance de matière discale intervertébrale. Le disque (200) comprend une matrice volumique sèche poreuse en fibres biocompatibles ou biorésorbables pouvant être entremêlées avec des molécules de glycosaminoglycan. La matrice est adaptée pour présenter in vivo un contour de surface extérieur sensiblement identique à celui d'un disque intervétébral naturel, de manière que ladite matrice établit une greffe servant de support au moins partiellement biorésorbable adaptée pour permettre la croissance intérieure de fibrochondrocytes intervertébraux. Une partie des molécules GAG peut assurer des liaisons transversales.

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