Protease inhibitors

Details Protease inhibitors Protease inhibitors

C - Chemistry, Metallurgy

07

K

530/7.02

C07K 5/02 (2006.01)

Patent

CA 1151643

ABSTRACT OF THE DISCLOSURE A process is provided herein for the preparation of an acidic protease inhibitor. The process involves allowing a compound of Image wherein X and Y are L-leucine or L-valine, or its salt, to react with an aluminum compound in a medium containing water and/or an alcohol, and further continuing the reaction after adjusting the pH of the system within a range of 4.5 to 7. The protease can stay for a long time in the stomach, has an action to protect ulcerated areas and retains the anti- ulcer effect for a long period of time.

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