Protease inhibitors

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C - Chemistry, Metallurgy

07

C

C07C 233/00 (2006.01) C07C 233/40 (2006.01) C07C 271/22 (2006.01) C07C 311/18 (2006.01) C07D 211/62 (2006.01) C07D 213/30 (2006.01) C07D 213/56 (2006.01) C07D 213/71 (2006.01) C07D 213/81 (2006.01) C07D 215/36 (2006.01) C07D 215/48 (2006.01) C07D 233/54 (2006.01) C07D 257/04 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2289602

The present invention provides bis-aminomethylcarbonyl compounds that are inhibitors of cysteine and serine proteases. The compounds are particularly useful for treating diseases in which excess cysteine protease activity has been implicated, including osteoporosis, periodontitis and arthritis.

L'invention porte sur des composés de bis-aminométhylcarbonyl inhibiteurs des protéases de la cystéine et de la sérine. Lesdits composés s'avèrent particulièrement utiles pour traiter les maladies impliquant un excès d'activité de la protéase de la cystéine, dont l'ostéoporose, la périodontite ou l'arthrose.

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