Protease-stable proteins

Details Protease-stable proteins Protease-stable proteins

C - Chemistry, Metallurgy

12

N

C12N 15/55 (2006.01) C11D 3/386 (2006.01) C11D 7/42 (2006.01) C12N 1/15 (2006.01) C12N 9/20 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2124316

2124316 9311254 PCTABS00022 A protein with improved stability against proteolytic degradation is provided, wherein one or more protease labile amino acid segments are substituted by protease non-labile amino acid segment(s). The protein to be stabilized is advantageously an enzyme, e.g. of microbial origin, such as a lipase, for instance a lipase derived from a strain of Humicola, e.g. H. lanuginosa, or Rhizomucor, e.g. R. miehei. The stabilized protein may be produced by recombinant DNA techniques and may advantageously be used for detergent purposes.

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