Protection of lyophilized betalactams from color formation

Details Protection of lyophilized betalactams from color formation Protection of lyophilized betalactams from color formation

A - Human Necessities

61

K

167/187

A61K 31/535 (2006.01) A61K 47/26 (2006.01)

Patent

CA 1164801

- Abstract - A stable preparation of a lyophilized .beta.-lactam antibacterlal containing a 7.beta.-( .alpha.carboxy-.alpha.-arylacetarmido)-7.alpha.-metiloxy-3- heterocyclic thiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylic acid (I) alkali metal salt as the antibactertal component and a sugar or sugar alcohol compound as the stabilizing agent. Image (I) (wherein Ar is a p-hydroxyaryl group and Het is a hetezocyclic group optionally substituted by an alkyl group) - 1 -

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