Protection of stem cells from cytotoxic agents by modulation...

Details Protection of stem cells from cytotoxic agents by modulation... Protection of stem cells from cytotoxic agents by modulation...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A01N 43/04 (2006.01) A61K 31/282 (2006.01) A61K 31/4745 (2006.01) A61K 31/505 (2006.01) A61K 31/52 (2006.01) A61K 31/70 (2006.01) A61K 31/704 (2006.01) A61K 31/7052 (2006.01) A61K 31/7064 (2006.01) A61K 31/7076 (2006.01) A61K 38/00 (2006.01) A61K 38/17 (2006.01) A61P 35/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2507581

Reagents that block the extracellular activation of .beta.-catenin are used to induce quiescence in normal stem cells, in order to reduce the killing of stem cells by anti-proliferative agents.

L'invention concerne des réactifs qui bloquent l'activation extracellulaire de la .beta.-caténine, utilisés pour induire une quiescence dans des cellules souches normales, afin de réduire l'élimination de cellules souches par des agents anti-prolifératifs.

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