C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/12 (2006.01) A61K 39/395 (2006.01) C07K 16/14 (2006.01)
Patent
CA 2580362
Anti-.beta.-1,3-glucan antibodies have been found to be protective against systemic fungal infection with Candida albicans. The present invention provides monoclonal antibodies that bind to .beta.-1,3-glucan, hybridoma cell lines producing the antibodies, compositions comprising the antibodies and methods of using such antibodies for treatment of microbial infections, particularly against Candida albicans and Aspergillus fumigatis infections. The antibodies of the present invention are not specific for .beta.-1,6-glucan.
La présente invention concerne des anticorps anti-ß-1,3-glucanes protégeant contre une infection fongique systémique à Candida albicans. Cette invention concerne des anticorps monoclonaux qui se lient à des lignées cellulaires d'hybridomes de ß-1,3-glucanes produisant des anticorps. L'invention concerne également des compositions comprenant les anticorps susmentionnés et des méthodes permettant d'utiliser de tels anticorps pour traiter des infections microbiennes, plus particulièrement des infections à Candida albicans et à Aspergillus fumigatis. Les anticorps décrit dans cette invention ne sont pas propres au ß-1,6-glucane.
Cassone Antonio
Torosantucci Antonella
Borden Ladner Gervais Llp
Cassone Antonio
Novartis Vaccines And Diagnostics Inc.
Torosantucci Antonella
LandOfFree
Protective anti-glucan antibodies with preference for... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Protective anti-glucan antibodies with preference for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Protective anti-glucan antibodies with preference for... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1733913