Protective antigens against parasites

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) C07K 14/435 (2006.01) C07K 16/18 (2006.01) C12P 21/08 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2172492

A putative protective antigen or fragment thereof against infections selected from the group consisting of Ostertagia circumcincta, Trichostrongylus colubriformis and Fasciola hepatica or related infections, being antigens selected from antigens having approximate molecular weights in the region of 26-36 and 91-105 kilodaltons, an antigen having an approximate molecular weight of 32-35 kilodaltons, and antigens having approximate molecular weights in the region of 28 kilodaltons, 32 kilodaltons, 37 kilodaltons, 42 to 100 kilodaltons, 54 to 55 kilodaltons and > 200 kilodaltons, respectively.

La présente invention concerne un antigène putatif ou un fragment d'antigène de protection contre les infections choisies parmi l'Ostertagia circumcincta le Trichostrongylus colubriformis et le Fasciola hepatica ou autres infections apparentées. Cet antigène est sélectionné parmi des antigènes dont les poids moléculaires approximatifs se situent entre 26 et 36 kilodaltons et 91 et 105 kilodaltons, un antigène présentant un poids moléculaire approximatif de 32-35 kilodaltons, et des antigènes dont les poids moléculaires approximatifs se situent autour de 28 kilodaltons, 32 kilodaltons, 37 kilodaltons, 42 à 100 kilodaltons, 54 à 55 kilodaltons et à plus de 200 kilodaltons, respectivement.

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