Protective complement proteins and age-related macular...

A - Human Necessities – 61 – K

Patent

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A61K 38/00 (2006.01)

Patent

CA 2638759

Methods for identifying a subject at risk for developing AMD are disclosed. The methods include identifying specific protective or risk polymorphisms or genotypes from the subject's genetic material. Therapeutic compositions and methods are also provided for delaying the progression or onset of the development of AMD in a subject, including treating a subject having signs and/or symptoms of AMD or who has been diagnosed with AMD.

La présente invention concerne des procédés permettant d'identifier un sujet risquant de développer une dégénérescence maculaire liée à l'âge (AMD). Les procédés consistent à identifier à partir du matériel génétique du sujet des polymorphismes ou des génotypes spécifiques protecteurs ou présentant un risque. L'invention porte aussi sur les compositions et les procédés thérapeutiques destinés à retarder la progression ou le début du développement de l'AMD chez un sujet, ce qui comprend également le traitement d'un sujet présentant des signes et/ou des symptômes de l'AMD ou chez qui l'on a diagnostiqué l'AMD.

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