C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/31 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2128415
2128415 9314634 PCTABS00024 The present invention includes a method for preventing or treating the toxic effects of a superantigen. A subject is treated with a molecule which interacts with specific V.beta. elements of T cells in a manner similar to that of a native superantigen. The molecules of the present invention are mutated or modified superantigens which elicit antibody production without inducing T cell proliferation.
Kappler John W.
Marrack Philippa
National Jewish Center For Immunology And Respiratory Medicine
Smart & Biggar
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