Protein and peptide sensors using electrical detection methods

Details Protein and peptide sensors using electrical detection methods Protein and peptide sensors using electrical detection methods

G - Physics

01

N

G01N 33/543 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2404492

The present invention provides an apparatus and methods for the electrical detection of molecular interactions between a probe molecule and a protein or peptide target molecule, but without requiring the use of electrochemical or other reporters to obtain measurable signals. The methods can be used for electrical detection of molecular interactions between probe molecules bound to defined regions of an array and protein or peptide target molecules which are permitted to interact with the probe molecules.

L'invention concerne un dispositif et des procédés de détection électrique d'interactions moléculaires entre une molécule sonde et une molécule cible, peptide ou protéine, sans qu'il soit nécessaire d'utiliser des marqueurs électrochimiques ou autres pour obtenir des signaux mesurables. On peut utiliser ces procédés dans la détection électrique d'interactions moléculaires entre des molécules sondes, liées à des régions définies d'un arrangement, et des molécules cibles, peptides ou protéines, lesquelles peuvent ainsi interagir avec les molécules sondes.

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