Protein and production thereof

Details Protein and production thereof Protein and production thereof

C - Chemistry, Metallurgy

12

P

530/13, 195/1.22

C12P 21/00 (2006.01) A61K 39/29 (2006.01) C07K 14/02 (2006.01) C12N 15/81 (2006.01) C12N 15/85 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1290713

Abstract A trypsin-like protease-resistant modified P31 protein having hepatitis B virus surface antigen activity and ability to bind polymerized human serum albumin as derived from a hepatitis B virus surface antigen P31 protein by such modification as to render at least one trypsin-like protease sensitive site thereof insensitive can be used as a vaccine for prevention of hepatitis B virus infections and as an antigen for diagnosis of hepatitis B virus infections.

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