C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/00 (2006.01) C07K 14/465 (2006.01) C07K 14/47 (2006.01) C12N 15/02 (2006.01) C12N 15/09 (2006.01) C12N 15/10 (2006.01) C12Q 1/70 (2006.01)
Patent
CA 2544764
The present invention provides a protein scaffold, such as an avian pancreatic polypeptide, that can be modified by substitution of two or more amino acid residues that are exposed on the alpha helix domain of the polypeptide when the polypeptide is in a tertiary form.
La présente invention concerne un squelette protéique tel qu'un polypeptide pancréatique aviaire qui peut être modifié par la substitution de deux ou plusieurs résidus d'acides qui sont exposés dans le domaine d'hélice alpha du polypeptide lorsque le polypeptide est sous une forme tertiaire.
Chin Jason W. K.
Rutledge Stacey E.
Schepartz Alanna S.
Schneider Tanya L.
Volkman Heather M.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Yale University
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