Protein c and endothelial protein c receptor polymorphisms...

Details Protein c and endothelial protein c receptor polymorphisms... Protein c and endothelial protein c receptor polymorphisms...

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) A61K 45/00 (2006.01) A61P 29/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2479968

The invention provides methods and kits for obtaining a prognosis for a patient having or at risk of developing an inflammatory condition. The method generally comprises determining a protein C and/or EPCR genotype(s) of a patient for a polymorphisms in the these genes, comparing the determined genotype with known genotypes for the polymorphism that correspond with the ability of the patient to recover from the inflammatory condition and identifying patients based on their prognosis. The invention also provides for methods of identifying other polymorphisms that correspond with the ability of the patient to recover from the inflammatory condition.

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