Protein complex and uses

Details Protein complex and uses Protein complex and uses

C - Chemistry, Metallurgy

12

N

C12N 9/12 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2673376

The present invention relates to a complex comprising two or more of the proteins S6K2, PKC.epsilon. and B-Raf. The invention also relates to antibodies that specifically bind to the complex, inhibitors of the complex and uses of the antibodies, inhibitors and complex in diagnosing and preventing chemoresistance in a patient.

L'invention se rapporte à un complexe comprenant au moins deux protéines parmi les protéines S6K2, PKC.epsilon. et B-Raf. L'invention concerne également des anticorps qui se lient spécifiquement au complexe, des inhibiteurs dudit complexe et des utilisations des anticorps, des inhibiteurs et du complexe dans le diagnostic et la prévention d'une chimiorésistance chez un patient.

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