Protein complexes and assays for screening anti-cancer agents

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 16/30 (2006.01) C07K 16/32 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2408213

Protein complexes containing a SKP2 binding protein (STAP1) are provided useful in identifying anti-cancer agents. Also provided are agents identified using the methods for use as therapeutics.

L'invention concerne des complexes protéiques renfermant une protéine de liaison SKP2( STAP1), que l'on utilise pour identifier des agents anticancéreux. Cette invention a également trait à des agents identifiés au moyen des méthodes utilisées en thérapie.

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