C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 9/10 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2493007
The present invention relates to the TIP60-transcriptional activator protein complex, which is a part of the beta-amyloid precursor protein (APP) processing pathway, component proteins of the said complexes, fragments and derivatives of the component proteins, and antibodies specific to the complexes. The present invention also relates to methods for use of these complexes and the interacting proteins in, inter alia, screening, diagnosis, and therapy, as well as to methods of preparing the complexes.
L'invention concerne le complexe de la protéine activatrice de la transcription de TIP60 qui est une partie de la voie de traitement de la protéine précurseur béta-amyloïde (APP), des protéines de composants desdits complexes, des fragments et des dérivés de celles-ci et des anticorps spécifiques des complexes. L'invention concerne également des procédés d'utilisation de ces complexes et des protéines à interaction dans les criblage, diagnostic et thérapie inter alia, ainsi que des procédés de préparation des complexes.
Bauer Andreas
Bowmeester Tewis
Drewes Gerard
Merino Alejandro
Bcf Llp
Cellzome Ag
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