C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/435 (2006.01) A61K 47/48 (2006.01) C12N 9/96 (2006.01)
Patent
CA 2155953
Protein conjugates with specific affinity to appropriate target cells, and more particularly to cancer cells, as well as their applications as anti-cancer medicament(cytolytic properties). Said protein conjugates of the type comprising a non specific portion and a portion having a particular affinity for a specific type of target cells, are characterized in that the portion having such particular affinity for a specific type of target cells is .alpha.-foetoprotein, and the non specific portion of said conjugate is selected in the group including the cytotoxic substances selected from animal toxins, plant toxins, cytolytic enzymes and low molecular weight active anti-cancer principles.
Kiselev Vsevolod
Nakachian Raymond
Severin Evgueni S.
Severin Serguei E.
Andreani Jean-Xavier
Borden Ladner Gervais Llp
Intromed Limited
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