Protein conjugates, compositions containing them and their...

Details Protein conjugates, compositions containing them and their... Protein conjugates, compositions containing them and their...

C - Chemistry, Metallurgy

07

K

C07K 14/435 (2006.01) A61K 47/48 (2006.01) C12N 9/96 (2006.01)

Patent

CA 2155953

Protein conjugates with specific affinity to appropriate target cells, and more particularly to cancer cells, as well as their applications as anti-cancer medicament(cytolytic properties). Said protein conjugates of the type comprising a non specific portion and a portion having a particular affinity for a specific type of target cells, are characterized in that the portion having such particular affinity for a specific type of target cells is .alpha.-foetoprotein, and the non specific portion of said conjugate is selected in the group including the cytotoxic substances selected from animal toxins, plant toxins, cytolytic enzymes and low molecular weight active anti-cancer principles.

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