Protein crosslinkers, crosslinking methods and applications...

C - Chemistry – Metallurgy – 08 – K

Patent

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Details

C08K 5/3415 (2006.01) A61K 47/42 (2006.01) A61L 24/10 (2006.01) A61L 31/06 (2006.01) A61L 31/16 (2006.01) C07K 1/02 (2006.01) C07K 1/107 (2006.01) C08H 1/00 (2006.01) C08J 3/075 (2006.01) C08J 3/24 (2006.01) C07K 14/75 (2006.01) C07K 14/76 (2006.01) C07K 17/00 (2006.01)

Patent

CA 2650473

Some aspects of this disclosure relate to a method for crosslinking a biological fluid comprising combining a biological fluid with a crosslinker to covalently crosslink proteins endogenous to the biological fluid to form a crosslinked gel. Examples of a biological fluid are blood, plasma, or serum.

Certain aspects de la présente invention concernent une méthode de réticulation d'un fluide biologique qui comprend la combinaison d'un fluide biologique avec un agent de réticulation afin de réticuler de façon covalente des protéines endogènes au fluide biologique pour former un gel réticulé. Des exemples de fluide biologique comprennent le sang, le plasma ou le sérum.

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