Protein-dimeric polysaccharide conjugate vaccine

Details Protein-dimeric polysaccharide conjugate vaccine Protein-dimeric polysaccharide conjugate vaccine

C - Chemistry, Metallurgy

07

K

C07K 14/00 (2006.01) A61K 39/102 (2006.01) A61K 39/116 (2006.01) A61K 39/385 (2006.01) A61K 47/48 (2006.01) C07K 14/22 (2006.01) C07K 14/315 (2006.01)

Patent

CA 2078359

18411 TITLE OF THE INVENTION PROTEIN-DIMERIC POLYSACCHARIDE CONJUGATE VACCINE ABSTRACT OF THE DISCLOSURE A conjugate immunogen, having polysaccharide moieties derived from bacterial sources, provides a multivalent vaccine with a low protein to polysaccharide ratio. The vaccine reduces complications associated with injection of protein immunogens due to pyrogenic responses, such as swelling and pain, and is particularly suitable for administration to infants.

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