Protein for inhibiting collagen-stimulated platelet aggregation

Details Protein for inhibiting collagen-stimulated platelet aggregation Protein for inhibiting collagen-stimulated platelet aggregation

C - Chemistry, Metallurgy

12

N

C12N 15/15 (2006.01) A61K 38/58 (2006.01) C07K 1/14 (2006.01) C07K 14/435 (2006.01) C07K 14/815 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2052486

1760H/2042a 18053 TITLE OF THE INVENTION PROTEIN FOR INHIBITING COLLAGEN-STIMULATED PLATELET AGGREGATION ABSTRACT OF THE DISCLOSURE A protein isolated from crude Haementeria officinalis extract which blocks stimulation of platelet aggregation by collagen. The protein has a molecular weight of approximately 16,000. A method of isolating the protein and using the protein to prevent or delay blood coagulation by blocking the stimulation of platelet aggregation by collagen is also described. The protein is useful in the prevention, prophylaxis, therapy and treatment of thrombotic diseases.

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