Protein formulation

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/96 (2006.01)

Patent

CA 2723007

An aqueous composition which comprises a protein or other biological molecule and also (i) optionally comprises one or more metal ions at a concentration of 0.01 to 20 mM; (ii) comprises excipients which which are weak ligands; and (iii) is substantially free of excipients which are medium-strength ligands or strong ligands.

L'invention concerne une composition aqueuse qui comprend une protéine ou une autre molécule biologique et également (i) qui comprend, facultativement, un ou plusieurs ions métalliques à une concentration allant de 0,01 à 20 mM, (ii) qui comprend des excipients qui sont des ligands faibles, et (iii) qui est sensiblement dépourvue d'excipients qui sont des ligands de force moyenne ou des ligands forts.

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