Protein having a transactivating property, vectors...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/49 (2006.01) A61K 39/395 (2006.01) C07K 14/16 (2006.01) C07K 16/10 (2006.01) C12N 5/10 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2056452

2056452 9015875 PCTABS00003 A protein having a molecular weight of approximately 15 kD and the ability to activate cell growth in trans is disclosed. This protein is referred to as the rap protein or viral protein R and produced by an active vpr gene. The active vpr gene and/or its gene product can be used to produce high levels of expression of a desired heterologous gene.

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