Protein kinase c-d inhibitors that protect against cellular...

Details Protein kinase c-d inhibitors that protect against cellular... Protein kinase c-d inhibitors that protect against cellular...

A - Human Necessities

61

K

A61K 38/04 (2006.01) A61K 38/16 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2698013

The invention relates to the use of .delta.PKC inhibitor peptides to treat brain injury, particularly traumatic brain injury (TBI). In one embodiment, peptide that specifically inhibit .delta.PKC are used to protect neurological tissue by promoting astrocyte proliferation.

L'invention concerne l'utilisation de peptides inhibiteurs de PKCd pour traiter les lésions cérébrales, en particulier les lésions cérébrales traumatiques (TBI). Dans un mode de réalisation, des peptides inhibant spécifiquement la PKCd sont utilisés pour protéger les tissus neurologiques en favorisant la prolifération des astrocytes.

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