Protein kinase c inhibitor

Details Protein kinase c inhibitor Protein kinase c inhibitor

C - Chemistry, Metallurgy

07

D

C07D 498/22 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2237221

This invention provides novel bis-indolylmaleimide macrocycle derivatives of formula (Ia), and solvates thereof. The invention further provides the preparation, pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.

L'invention concerne des nouveaux dérivés de macrocycles de bis-indolylmaléimide de la formule (Ia) et des solvates de ces derniers. L'invention traite aussi de la préparation, de formulations pharmaceutiques et de procédés d'utilisation pour inhiber la protéine Kinase C chez des mammifères.

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