Protein kinase c inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 498/22 (2006.01) A61K 31/395 (2006.01) A61K 31/70 (2006.01) C07C 43/174 (2006.01) C07C 43/178 (2006.01) C07D 471/22 (2006.01) C07D 487/22 (2006.01) C07D 513/22 (2006.01) C07F 7/18 (2006.01) C07H 15/26 (2006.01) C07H 17/00 (2006.01)

Patent

CA 2137203

This invention provides novel bis-indolemaleimide macrocycle derivatives of the formula: (see formula I) The invention further provides the preparation, pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.

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