Protein kinase c inhibitors and uses thereof

Details Protein kinase c inhibitors and uses thereof Protein kinase c inhibitors and uses thereof

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01) A61K 31/407 (2006.01) A61K 31/506 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) A61P 29/00 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2749195

This disclosure concerns compounds which are useful as inhibitors of protein kinase C (PKC) and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC. This disclosure also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

La présente invention concerne des composés qui sont utiles en tant qu'inhibiteurs de la protéine kinase C (PKC) et qui sont utiles pour le traitement d'une variété de maladies et de troubles médiés ou entretenus par l'activité de la PKC. La présente invention concerne également des compositions pharmaceutiques qui comprennent ces composés, des procédés d'utilisation de ces composés dans le traitement de différentes maladies et de différents troubles, des procédés de préparation de ces composés et des intermédiaires utiles dans ces procédés.

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