Protein kinase modulation by hops and acacia products

A - Human Necessities – 61 – K

Patent

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A61K 38/43 (2006.01) A61K 36/00 (2006.01)

Patent

CA 2632684

Botanical compounds to modulate kinase activity are disclosed. The compounds and methods disclosed also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively. The compositions contain at least one fraction isolated or derived from hops or Acacia.

L'invention concerne des composés d'origine végétale destinés à moduler l'activité kinase. Les composés et les méthodes de l'invention permettent également d'inhiber l'expression de COX-2, d'inhiber sélectivement la synthèse de prostaglandines dans des cellules cibles, et d'inhiber sélectivement la réponse inflammatoire. Ces compositions contiennent au moins une fraction isolée ou dérivée du houblon ou d'Acacia.

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