Protein kinase modulators

Details Protein kinase modulators Protein kinase modulators

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4745 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2716755

The invention relates in part to molecules having certain biological activities that include, but are not limited to, inhibiting cell proliferation, modulating protein kinase activity and modulating polymerase activity. Molecules of the invention can modulate Pim kinase activity and/or FMS-like tyrosine kinase (Ht) activity. The invention also relates in part to methods for using such molecules.

Linvention concerne notamment des molécules possédant certaines activités biologiques qui comprennent sans caractère limitatif linhibition de la prolifération cellulaire, la modulation de lactivité de protéines kinases et la modulation de lactivité de polymérases. Les molécules de linvention peuvent moduler lactivité des kinases Pirn et/ou lactivité des tyrosines kinases (Ht) du type FMS. Linvention concerne également notamment des procédés dutilisation de ces molécules.

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