A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61K 9/00 (2006.01) A61K 39/21 (2006.01) A61K 39/39 (2006.01)
Patent
CA 2264646
A protein-lipid vesicle that can be used to make an autogenous vaccine comprises patient-specific antigen, adjuvant or immunomodulator, and lipid carrier. In addition, a negatively charged lipid component is desirably included. The autogenous vaccine is useful to treat individuals with chronic diseases, including chronic infectious diseases and neoplasias. The chronic infectious diseases that can be treated include disease caused by infection with human immunodeficiency viruses.
L'invention se rapporte à une vésicule de protéines-lipides, qui peut être utilisée pour fabriquer un vaccin autogène, lequel comprend un antigène spécifique à un patient, un adjuvant ou un immunomodulateur et un porteur de lipides. En outre, un composant lipide chargé négativement est de préférence inclus. Le vaccin autogène est utilisé pour traiter des maladies chroniques, dont des maladies chroniques infectieuses et des néoplasies. Les maladies infectieuses chroniques qui peuvent être traitées comprennent des maladies causées par une infection par des virus d'immunodéficience humaine.
Denny Thomas N.
Feketeova Eleonora
Gould-Fogerite Susan
Mannino Raphael J.
Oleske James M.
Albany Medical College
Gowling Lafleur Henderson Llp
University Of Medicine And Dentistry Of New Jersey
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