A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 9/127 (2006.01) A61K 38/13 (2006.01) A61K 38/28 (2006.01) A61K 39/145 (2006.01) A61K 39/155 (2006.01) A61K 39/21 (2006.01) A61K 39/39 (2006.01) A61K 47/48 (2006.01)
Patent
CA 2169297
The present disclosure relates to a vaccine comprising a biologically effective dosage amount of a protein- or peptide-cochleate, wherein said protein- or peptide-cochleate comprises the following components: a) a protein or peptide component to which an immune response is elicited, b) a negatively charged lipid component, and c) a divalent cation component. The present invention also provides a method of immunizing a host, comprising administering a biologically effective amount of the above-described protein- or peptide-cochleate. Advantageously, the vaccine can be administered orally.
L'invention concerne un vaccin comprenant une quantité de dosage biologiquement efficace d'un cochléate protéique ou peptidique qui contient les composants suivants: a) une protéine ou un peptide face à laquelle/auquel on souhaite une réponse immunitaire, b) un lipide chargé négativement, et c) un cation divalent. Cette invention concerne aussi un procédé permettant d'immuniser un hôte et consistant à administrer une quantité biologiquement efficace de ce cochléate protéique ou peptidique. Ce vaccin présente l'avantage d'être administrable par la voie orale.
Gould-Fogerite Susan
Mannino Raphael James
Albany Medical College
Gould-Fogerite Susan
Gowling Lafleur Henderson Llp
Mannino Raphael James
University Of Medicine And Dentistry Of New Jersey
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