Protein phosphatase 2a-activating agents

Details Protein phosphatase 2a-activating agents Protein phosphatase 2a-activating agents

C - Chemistry, Metallurgy

07

D

C07D 311/72 (2006.01) A61K 31/353 (2006.01) A61P 35/00 (2006.01) C07F 9/655 (2006.01)

Patent

CA 2758823

Tocopheryl succinate derivatives according to formula (I) are described. These compounds increase the activity of protein phosphatase 2A, can be included in pharmaceutical compositions, and can be used for the treatment of androgen receptor-dependent cancers such as prostate cancer.

L'invention porte sur des dérivés de succinate de tocophéryle selon la formule (I). Ces composés augmentent l'activité de la protéine phosphatase 2A, peuvent être compris dans les compositions pharmaceutiques, et peuvent être utilisés pour le traitement de cancers dépendants du récepteur aux androgènes tels que le cancer de la prostate.

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