A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/24 (2006.01) A61K 31/00 (2006.01) A61K 31/198 (2006.01) A61K 45/06 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2460057
A protein prenyl transferase inhibitor is used in the treatment of neuroinflammatory disease such as MS, uveitis, alzheimers or neuroAIDS. The inhibitor may be a combination of a farnesyl transferase inhibitor and a geranylgeranyl transferase inhibitor. Preferably, FTI-277 and/or GGTI-298 is employed.
L'invention concerne un inhibiteur de prényl-transférase protéique utilisé dans le traitement de maladies neuro-inflammatoires telles que la sclérose en plaques, l'uvéite, la maladie d'Alzheimer ou le neuro-sida. Cet inhibiteur peut être une combinaison d'un inhibiteur de farnésyl-transférase et d'un inhibiteur de géranylgéranyl-transférase. On utilise de préférence FTI-277 et/ou GGTI-298.
Adamson Peter
Greenwood John
Institute Of Ophthalmology
Macrae & Co.
LandOfFree
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