C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) C07K 1/107 (2006.01) C07K 1/30 (2006.01) C07K 1/36 (2006.01) C12N 9/00 (2006.01) C12N 9/56 (2006.01)
Patent
CA 2125853
2125853 9313125 PCTABS00024 A process for the microbial production of a protein susceptible to inactivation in a fluid production medium by constinuously and reversibly protecting said protein against said inactivation during the production stage, separating the protein from the production medium, deprotecting the protein, and recovering the protein product. The process is especially useful for obtaining substantially increased yields of the protein in question by continuously precipitating said protein.
Joergensen Per L.
Mikkelsen Jan M.
Nielsen Torben K.
Pedersen Poul E.
Petersen Joergen
Mccarthy Tetrault Llp
Novo Nordisk A/s
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