Protein rib, a cell surface protein that confers immunity to...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/31 (2006.01) A61K 39/09 (2006.01) C07K 14/315 (2006.01) C07K 16/12 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2158658

This invention relates to a new protein, designating Rib, and subfragments, multiples or variants thereof, which confers protective immunity against infection with many group B streptococcal strains, in particular those of serotype III. The invention includes a procedure for purification of the protein, a procedure for preparation of highly specific antibodies, a reagent kit, a DNA sequence encoding the protein and a pharmaceutical composition comprising the protein or fragments or variants thereof.

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