Protein scaffolds for antibody mimics and other binding...

Details Protein scaffolds for antibody mimics and other binding... Protein scaffolds for antibody mimics and other binding...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 14/525 (2006.01) C07K 14/78 (2006.01) C07K 16/00 (2006.01) C07K 16/24 (2006.01) C07K 17/00 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2418835

Disclosed herein are proteins that include an immunoglobulin fold and that can be used as scaffolds. Also disclosed herein are nucleic acids encoding such proteins and the use of such proteins in diagnostic methods and in methods for evolving novel compound-binding species and their ligands.

La présente invention concerne des protéines qui comprennent un pli d'immunoglobuline et qui peuvent être utilisées comme échafaudages protéiniques internes. L'invention traite aussi d'acides nucléiques codant ces protéines et de l'utilisation de ces protéines dans des procédés de diagnostique et dans des procédés de développement de nouvelles espèces de liaison aux composés et de leurs ligands.

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