C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2517802
Using gene expression profiling, the present Invention identifies Protein tyrosine phosphatase IVA member 1 (PRL-1) as a diagnostic marker and therapeutic target for pancreatic cancer. The Invention therefore provides methods for prediction and detection of PRL-1 associated cancers, and evaluation of inhibitors of PRL-1. The Invention also provides a method of treating or preventing pancreatic cancer in a subject.
L'invention met en application le profilage de l'expression génique afin d'identifier un élément (1) de protéine tyrosine phosphatase IVA (PRL-1) en tant que marqueur diagnostique et cible thérapeutique pour le cancer du pancréas. Elle concerne, par conséquent, des méthodes servant à prédire et à détecter des cancers associés à PRL-1, ainsi qu'à évaluer des inhibiteurs de PRL-1. Elle concerne également une méthode de traitement ou de prévention du cancer du pancréas.
Bearss David
Farnsworth Amanda L.
Han Haiyong
Vankayalapati Hariprasad
von Hoff Daniel
Arizona Board Of Regents On Behalf Of The University Of Arizona
Bearss David
Farnsworth Amanda L.
Goudreau Gage Dubuc
Han Haiyong
LandOfFree
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