Proteins expressed in nk cells

C - Chemistry – Metallurgy – 12 – N

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C12N 15/09 (2006.01) A61K 45/00 (2006.01) A61P 1/16 (2006.01) A61P 11/06 (2006.01) A61P 31/12 (2006.01) A61P 31/14 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) A61P 37/06 (2006.01) A61P 37/08 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/00 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2540701

By analyzing expression frequency in purified immunocytes, NKIR gene expressed specifically in natural killer (NK) cells is successfully found out. This NKIR gene encodes a receptor and an agonist or an antagonist to the receptor can be identified with the use of the receptor.

Par l'analyse de la fréquence d'expression dans des immunocytes purifiés, on découvre le gène NKIR exprimé spécifiquement dans des cellules tueuse naturelles (NK). Ce gène NKIR code un récepteur et, un agoniste ou un antagoniste de ce récepteur peut être identifié via ce récepteur.

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