Proteins for use in diagnosing and treating infection and...

A - Human Necessities – 61 – K

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A61K 38/57 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61K 39/12 (2006.01) A61P 31/18 (2006.01) G01N 33/569 (2006.01) C07K 14/81 (2006.01)

Patent

CA 2668284

The present invention describes a composition comprised on cystatin A and at least one histone used in diagnostic tools and for the treatment of diseases associated with reduced T helper cell counts such as HIV-I infection, AIDS, ARC, multiple sclerosis, chronic fatigue syndrome, heumatoid arthritis, Alzheimer's disease, dermatitis, type 1 diabetes mellitus, colitis, inflammatory bowel disease / irritable bowel syndrome, Crohn's disease, Psoriasis, Chronic obstructive pulmonary disease, System lupus erythematosus, transplant rejection and cancer.

L'invention concerne une composition contenant une cystatine A et au moins une histone, utilisée dans des outils diagnostiques et dans le traitement de maladies associées à une numération réduite de lymphocytes T auxiliaires, telles que l'infection à VIH-1, le sida, le complexe lié au sida, la sclérose en plaques, le syndrome de fatigue chronique, la polyarthrite rhumatoïde, la maladie d'Alzheimer, la dermatite, le diabète sucré de type 1, la colite, la maladie/le syndrome intestinal inflammatoire, la maladie de Crohn, le psoriasis, la maladie pulmonaire obstructive chronique, le lupus érythémateux systémique, le rejet de greffe et le cancer.

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