Proteins having fibrinolytic and coagulation-inhibiting...

Details Proteins having fibrinolytic and coagulation-inhibiting... Proteins having fibrinolytic and coagulation-inhibiting...

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/36 (2006.01) A61K 38/48 (2006.01) A61K 38/49 (2006.01) A61K 38/58 (2006.01) C07K 14/815 (2006.01) C07K 19/00 (2006.01) C12N 9/72 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2162986

Proteins having fibrinolytic and coagulation-inhibiting properties are described, which are linked at the N- and/or C-terminal end of the plasminogen-activating amino acid sequence to a thrombin- or factor Xa-inhibiting amino acid sequence. The proteins, which are produced by genetic engineering, are suitable as thrombolytic agents.

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