C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/445 (2006.01) A61K 39/002 (2006.01) C07K 16/20 (2006.01) C12N 5/12 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2410051
The present invention provides the RSP-1 and RSP-2 proteins which are involved in the cytoadhesion of P. falciparum during ring-stage infection of erythrocytes, antibodies which bind to the proteins, methods of screening for a P.falciparum infection, methods of determining the infective stage of P.falciparum and vaccines for protecting individuals from Plasmodium sp. infections.
L'invention concerne des protéines RSP-1 et RSP-2 qui interviennent dans la cytoadhésion de P. falciparum durant l'infection, au stade annulaire, d'érythrocytes, des anticorps se liant aux protéines, des méthodes de dépistage pour une infection au P. falciparum, ainsi que des méthodes de détermination du stade infectieux de P. falciparum, et des vaccins pour la protection de sujets contre des infections d'espèces de Plasmodium.
Buffet Pierre
Gysin Jurg
Pouvelle Bruno
Scherf Artur
Centre National de La Recherche Scientifique
Institut Pasteur
Robic
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