Proteins s polypeptides and uses thereof

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 21/08 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61K 38/36 (2006.01) A61K 39/395 (2006.01) A61P 7/02 (2006.01) C07K 1/22 (2006.01) C07K 7/08 (2006.01) C07K 14/435 (2006.01) C07K 14/745 (2006.01) C07K 16/18 (2006.01) C07K 16/36 (2006.01) C07K 17/00 (2006.01) G01N 33/543 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2112701

The invention describes protein S polypeptides and anti-PS antibodies capable of inhibiting the binding of proteins to C4BP. The peptides and antibodies are useful in diagnostic methods and systems for purifying or detecting free protein S. In ad-dition, the polypeptides are useful in therapeutic methods as an anti- coagulant.

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