C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/39.1, 195/1.
C12N 15/12 (2006.01) A61K 38/37 (2006.01) C07K 14/755 (2006.01) C07K 16/36 (2006.01) C12N 1/00 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1341208
A protein having biological activity of Factor VIII, wherein the amino acid sequence of the protein essentially corresponds to the amino acid sequence of Factor VIII except for (a) a deletion of the amino acids Ser-741 through Ser-1637 and a deletion of at least part of the amino acids Lys-713 through Arg-740; (b) optionally a deletion of the amino acids Gln-1638 through Ile-1668, or part of them; and (c) optionally an insertion of a linking group comprising at least one amino acid.
569359
Pannekoek Hans
Van Leen Robert Willem
Van Ooyen Albert Johannes Joseph
Verbeet Martinus Phillipus
Baxter Aktiengesellschaft
Gist - Brocades N.v.
Osler Hoskin & Harcourt Llp
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