C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/14 (2006.01) A61K 31/194 (2006.01) A61K 31/444 (2006.01) A61K 31/496 (2006.01) A61P 25/28 (2006.01) A61P 31/12 (2006.01) C07C 59/70 (2006.01) C07D 401/14 (2006.01)
Patent
CA 2446380
The present invention relates to compounds and pharmaceutical compositions which are proteomimetic and to methods for inhibiting the interaction of an alpha-helical protein with another protein or binding site. Methods for treating diseases or conditions which are modulated through interactions between alpha helical protein and their binding sites are other aspects of the invention.
L'invention concerne des composés et des compositions pharmaceutiques protéomimétiques, et des procédés relatifs à l'inhibition de l'interaction qui fait intervenir une protéine alpha-hélicoïdale et une autre protéine ou un autre site de liaison. Par ailleurs, l'invention concerne des procédés relatifs au traitement de maladies ou d'affections modulées par les interactions qui font intervenir les protéines alpha-hélicoïdales et leurs sites de liaison.
Ernst Justin
Hamilton Andrew D.
Orner Brendan
Gowling Lafleur Henderson Llp
Yale University
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